3DChromoTwist

Explore how chromatin folds in 3D using puzzles inspired by real interaction data. Build intuition for spatial genome organization through hands-on challenges.

Preview 3DChromoTwist
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How it works

From interaction maps to 3D insight

Turn Hi-C interaction patterns into a playable 3D reconstruction challenge. Learn the logic behind modern genomics tools—by doing.

1
Start with interaction clues
Contact maps hint which genomic regions are close in 3D.
2
Twist & fold the chromosome
Drag, rotate, and reposition fragments to satisfy constraints.
3
Score & learn
Iterate with feedback and build spatial intuition over time.

Key Features

About the project
🧬
Real Scientific Data
Built using real chromatin interaction datasets.
🎮
Gamified Learning
Solve 3D reconstruction puzzles through interactive challenges.
📚
Research-Informed Design
Designed to teach spatial genome organization concepts.
🏆
Competitive Leaderboard
Track progress and compete with peers.

Who is it for?

Meet the team

Built for learners and educators who want an intuitive bridge between genomics data and 3D structure.

  • Undergraduate students
  • Computational biology learners
  • Genomics educators
  • AI + Bioinformatics enthusiasts

3D Genome Reconstruction

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